Sample Size in Animal Studies (The number of laboratory animals in a Research study)

Before interventional clinical studies in humans, researchers usually perform preclinical studies in vitro or in vivo to evaluate the initial efficacy, toxicity, and pharmacokinetics of interventions. Sample size determination in animal studies is necessary both in terms of correct and scientific inference and in terms of ethics. Therefore, the purpose of this paper is a brief description of how to determine the sample size in a study on laboratory animals.

کلیدواژه ها:

Laboratory animals ، Sample size ، Study power ، Laboratory studies ، حیوانات آزمایشگاهی ، حجم نمونه ، توان مطالعه ، مطالعات آزمایشگاهی